What is indicated by the prefix "macro-"?

The prefix "macro-" signifies something that is large or on a grand scale. It originates from the Greek word "makros," which means large or long. In medical terminology and related fields, "macro-" is commonly used to describe conditions, structures, or organisms that are large or that involve large-scale processes. For instance, "macrophage" refers to a large type of white blood cell that engulfs and digests cellular debris and pathogens, indicating the size and function of the cell. This prefix is often contrasted with "micro-," which denotes smallness. Thus, the option indicating "large" aligns perfectly with the established meaning of the prefix.